Tingtao Chen
P.I. / Professor
+86-139 7919 6862
chentingtao1984@163.com
AFFILIATIONS:
1. Vice Dean, School of Pharmacy, Jiangxi Medical College, Nanchang University (NCU).
2. Vice Dean, Institute of Translational Medicine, Jiangxi Medical College, NCU.
3. Director, Jiangxi Province Key Laboratory of Bioengineering Drugs, Institute of Translational Medicine, Jiangxi Medical College, NCU.
EDUCATION:
1. Ph.D., Food Science and Engineering, Nanchang University (09/2010 - 07/2013).
2. M.S., Zoology, Southwest University (09/2006 - 07/2009).
3. B.S., Sericulture, Shandong Agricultural University (09/2002 - 07/2006).
RESEARCH INTERESTS
1. Probiotics/prebiotics/postbiotics and their innovational applications in food supplementary and biomedicine.
2. Translational research of human microbiome.
3. Engineering bacteria and exploring their potential as live biotherapeutic products.
4. Development of probiotic products.
GRANT SUPPORTS:
1. National Natural Science Foundation of China, 2025-2028.
2. National Key R&D Program of China (Sub-project Leader, Grant No. 2024YFA1307103), 2025-2029.
3. "Food+" Interdisciplinary Cultivation Program, 2025-2030, NCU.
4. Over 40 Industry Collaboration Projects.
5. Jiangxi Provincial "Double-Thousand Plan" (High-End Scientific and Technological Innovation Talent Project), 2019-2024.
SELECTIVE PUBLICATIONS:
1. Tingtao Chen#*, Qingwei Zeng#, Tangchang Xu, Xinyue Qi, Kaiyi Li, Jing Wei, Liang Hao*. Synovial Fluid-derived Micrococcus luteus G18 Exacerbates Osteoarthritis Progression By Promoting Chondrocyte Degradation Via TLR2/JNK/AP-1 Signaling Pathway. Advanced Science, 2025, Accepted.
2. Rongli Liu#, Yangwei Ou, Lin Chen, Ying Hu, Linghan Zou, Yourong Wang, Danyi Zhao Yurun Pei, Xiaoyang li, Tingtao Chen*, Qi Chen*. Enhancing immunoassay sensitivity via genetic engineering of helper phage or phagemid for nanobodies high-efficiency display on recombinant M13 phage probes. Biosensors and Bioelectronics, 2025, Accepted.
3. Jie You#, Wu Liu#, Yuxiong Huang, Di Zhu, Xuan Xu, Yufan Wang, Jianying Chen, Qingling Yang, Tangchang Xu, Weijun Chen, Yifeng Yu*and Tingtao Chen*. Akkermansia muciniphila PROBIO ameliorates overweight via gut microbiota modulation：a randomized controlled trial. Food Science and Human Wellness, 2025, Accepted.
4. Xuanqi Zhao#, Qifa Huang#, Yujuan Liu#, Xia He, Weijun Chen, Yan Liu, Lihong Gan, Jing Wei, Hongyan Zhang* and Tingtao Chen*. Harnessing dual-channel probiotics to synergistically correct intestinal and vaginal dysbiosis after antibiotic disrupt ion. npj Biofilms and Microbiomes, 2025, 11(1): 174.
5. Xiaoni Han#, Hui Liu#, Kaige Zhang#, Yuyu Zeng, Peng Liu, Lihong Gan, Li Zheng, Zhiguo Liu, Nian Fang* and Tingtao Chen*. Lactiplantibacillus plantarum MH-301 reduces Helicobacter pylori treatment-related adverse events via gut-vaginal axis: a randomized, double-blind, placebo-controlled trial. Journal of Infection, 2025, 106539.
6. Tangchang Xu, Xiaoyun Wu, Yifei Zhang, Yujie Cai, Xinfeng Zhang, Qingwei Zeng, Jie Luo, Jing Wei & Tingtao Chen*. L-Tryptophan metabolized by Bifidobacterium pseudocatenulatum NCU-08 delays aging in SAMP8 mice by activating the Sirt1/P53/P21/Rb signaling pathway. Aging Cell, 2025, 24(9): e70166.
7. Dexi Zhou#, Shengjie Li#*, Yufan Wang, Zhanghua Qi, Xuan Xu, Jing Wei, Qiong Liu* and Tingtao Chen*. Hypoglycemic effect of C. butyricum-pMTL007-GLP-1 engineered probiotics on type 2 diabetes mellitus. Gut Microbes, 2025, 17(1): 2447814.
8. Wu Liu#, Jingyu Wang, Heng Yang, Congcong Li, Wanqi Lan, Tingtao Chen* and Yanhua Tang*. The Metabolite Indole‐3‐Acetic Acid of Bacteroides Ovatus Improves Atherosclerosis by Restoring the Polarisation Balance of M1/M2 Macrophages and Inhibiting Inflammation. Advanced Science, 2025, 2513010.
9. Qingwei Zeng#, Zhanghua Qi, Xia He, Chuanlin Luo, Jianing Wen, Jing Wei, Fenfang Yue, Xuanqi Zhao, Hong Wei* and Tingtao Chen*. Bifidobacterium pseudocatenulatum NCU-08 ameliorated senescence via modulation of the AMPK/Sirt1 signaling pathway and gut microbiota in mice. Food & Function, 2024, 15(8): 4095-4108.
10. Xinyue Hu, Xuan Xu, Xiangdi Zeng, Rui Jin, Shengnan Wang, Huifu Jiang, Yuwen Tang, Guanxiang Chen, Jing Wei, Tingtao Chen*, and Qi Chen*. Gut microbiota dysbiosis promotes the development of epithelial ovarian cancer via regulating Hedgehog signaling pathway. Gut Microbes, 2023, 15(1): 2221093.
MORE INFORMATION
https://orcid.org/0000-0002-0506-8536.
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