Qi Chen
Basic Information：
Name: Chen Qi Hometown: Zhangshu City, Jiangxi Province
Email: qichen@ncu.edu.cn Title: Associate Researcher
Supervisor Type: Master’s Supervisor
Courses Taught: Advances in Translational Medicine
Research Interests：
Nanobody development and engineering, phage display technology, immunoassay techniques
Education Background：
Sep 2014 – Jun 2018: China Agricultural University, Agricultural Engineering, Ph.D. (Supervisors: Academician Wang Maohua & Prof. Lin Jianhan)
Sep 2016 – Sep 2017: Clemson University, Mechanical Engineering, Joint Ph.D. (Supervisor: Prof. Xuan Xiangchun)
Sep 2011 – Jun 2014: Nanchang University, Microbiology, Master’s (Supervisors: Associate Prof. Wan Cuixiang & Researcher Xiong Yonghua)
Work Experience：
May 2022 – Present: Nanchang University, Associate Researcher
Jul 2018 – May 2022: Hainan University, Lecturer
Academic Affiliations：
Deputy Director, Jiangxi Provincial Key Laboratory of Biopharmaceuticals
Peer Review Expert, National Natural Science Foundation of China
Reviewer for renowned journals including Biosensors and Bioelectronics, Food Analytical Methods, Analysts, and Journal of Food and Biotechnology
Key Achievements：
Principal Investigator of two National Natural Science Foundation projects, five provincial/ministerial-level funds, and two university-level funds.
Published over 30 papers as first author or corresponding author in prestigious journals such as Biosensors and Bioelectronics, Analytical Chemistry, and Food Chemistry.
一、Presided Projects
1、National Natural Science Foundation of China (NSFC) Youth Fund Project: "Homogeneous Competitive Immunoassay for the Detection of Ochratoxin A in Coffee Based on Bioluminescence Resonance Energy Transfer" (Project No. 31901800), 240,000 CNY, Presided.
2、National Natural Science Foundation of China (NSFC) Regional Fund Project: "Study on a Continuous Directed Evolution System for Nanobodies in Bacteria Based on EvolvR Technology and Phage Display" (Project No. 32260623), 330,000 CNY, Presided.
3、Jiangxi Province "Double Thousand Plan": "Construction of an Efficient Nanobody Development System and Its Application in In Vitro Diagnostics" (Project No. 2021LQCQ0703), 1,000,000 CNY, Presided.
4、Jiangxi Provincial Natural Science Foundation Youth Project: "Development of a Nanobody-Based Immunochromatographic Test Strip for Bladder Cancer Diagnosis" (Project No. 20224BAB216058), 100,000 CNY, Presided.
二、Recent Representative Papers
1、Danyi Zhao, Mai Hu, Chenghao Hu, Di Wang, Hailun Chen, Yangwei Ou, Rongli Liu, Xiaoyang Li, Long Wu, Peng Liu*, Zhiwei Shen*, Qi Chen*. Multivalent bifunctional nanobody to enhance the sensitivity of direct competitive chemiluminescence immunoassay for the detection of microcystin LR in lake water[J]. Talanta, 2025, 283: 127080;
2、Long Wu*, Luyao Jiao, Danni Xue, Yueqing Li, Yu Han, Wei Ouyang, Qi Chen*.Nanozyme and bifunctional nanobody-based colorimetric-SERS dual-mode Immunosensor for microcystin-LR detection[J]. Food Chemistry, 2025, 464: 141574;
3、Kunlu Bao, Xing Liu, Zilong Liu, Hongmei Cao, Long Wu, Qi Chen*.Dual improved enzyme-linked immunosorbent assay based on multivalent bifunctional nanobody and polymerized horseradish peroxide for the ultrasensitive detection of Ochratoxin A in coffee samples[J]. Journal of Food Composition and Analysis, 2024, 136: 106788;
4、Xiao Dai#, Qi Chen#, Jia Hu, Yunkai Fan, Ying Xiong, Xiaoyang*.Selective removal of microcystin from eutrophic water by a nanobody-metal hybrid photocatalyst[J]. Chemical Engineering Journal, 2025, 506: 159993;
5、Rongli Liu1, Yangwei1, Lin Chen, Ying Hu, Linghan Zou, Yourong Wang, Danyi Zhao, Yurun Pei, Xiaoyang li, Tingtao Chen*, Qi Chen*.Enhancing immunoassay sensitivity via genetic engineering of helper phage or phagemid for nanobodies high-efficiency display on recombinant M13 phage probes[J]. Biosensors and Bioelectronics, 2026, 294: 118219.
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