
姓名:赖俊汕
职称:特聘研究员
邮箱:Laijsh13@qq.com
籍贯:江西瑞金
导师类型:博士生导师
主讲课程:
个人主页:
致力于以下领域的研究,并探索它们在药物合成中的应用:
1. 不对称催化化学:手性催化剂参与的不对称催化反应研究
2. 催化剂固载与连续流化学:小分子手性催化剂的设计与固载,以及在连续流化学中的应用
3.人工智能(AI)不对称催化:AI辅助与指导的不对称催化反应发现与设计,以及催化剂设计
4. 有机电化学与有机合成方法学开发
2025.3-至今 | 南昌大学 | 药物化学 | 博士生导师、特聘研究员 |
2021.5-2025.03 | UBC (加拿大) | AI有机催化化学 | 博士后 |
2023.6-2023.8 | MPI-Kofo (德国) | 有机催化化学 | 访问博士后 |
2016.10-2020.11 | ICIQ, URV (西班牙) | 固载催化化学 | 博士 |
2018.6-2018.9 | Cornell University (美国) | 有机电化学 | 访问博士生 |
2013.9-2016.6 | 兰州大学 | 有机化学 | 硕士 |
2009.9-2013.6 | 南昌大学 | 药学 | 学士 |
2021.5-2025.3 UBC Postdoctoral Research Fellow
2020 URV 优秀博士生(CUM LAUDE)
2017.4-2020.11 Ministerio FPI grant
2016.10-2017.4 ICIQ PhD Fellowship Programme
2016年兰州大学优秀毕业生
2015年研究生国家奖学金
2014年研究生国家奖学金
2014年兰州大学三好研究生
2013年兰州大学一等学业奖学金
发表论文
1. Junshan Lai, Benjamin List*, Jolene Reid*. Bis-indole chiral architectures for asymmetric catalysis. Nat. Commun. 2025, 16, 3676. (IF=14.7/Q1)
2. Isaiah O. Betinol§; Junshan Lai§; Saumya Thakur; Jolene Reid*. A Data-Driven Workflow for Assessing and Predicting Generality in Asymmetric Catalysis. J. Am. Chem. Soc. 2023, 145, 12870–12883. (并列第一作者IF=16.38/Q1)
3. Junshan Lai, Jolene Reid*. Interrogating the thionium hydrogen bond as a noncovalent stereocontrolling interaction in chiral phosphate catalysis. Chem. Sci. 2022, 13, 11065-11073. (IF=9.97/Q1)
4. Junshan Lai; Jolene P. Reid*. A Bulky Imidodiphosphorimidate Brønsted Acid Enables Highly Enantioselective Prins-semipinacol Rearrangements. ACS Catal. 2024, 14,8518-8527.(IF=13.70/Q1)
5. Junshan Lai, Mauro Fianchini, Miquel A. Pericàs*. Development of Immobilized SPINOL-Derived Chiral Phosphoric Acids for Catalytic Continuous Flow Processes. Use in the Catalytic Desymmetrization of 3,3-Disubstituted Oxetanes. ACS Catal. 2020, 10, 14971-14983. (IF=13.70/Q1)
6. Junshan Lai, Miquel A. Pericàs*. Manganese/Copper Co-catalyzed Electrochemical Wacker–Tsuji-Type Oxidation of Aryl-Substituted Alkenes. Org. Lett. 2020, 22, 7338-7342. (IF=6.07/Q1)
7. Junshan Lai, Rifahath M. Neyyappadath, Andrew D. Smith, Miquel A. Pericàs. Continuous flow preparation of enantiomerically pure binol(s) by acylative kinetic resolution. Adv. Synth. Catal. 2020, 362, 1370-1377. (IF=5.8/Q1)
8. Junshan Lai, Sonia Sayalero, Alessandro Ferrali, Laura Osorio-Planes, Fernando Bravo, Carles Rodríguez-Escrich, Miquel A. Pericàs. Immobilization of cis-4-hydroxydiphenylprolinol silyl ethers onto polystyrene. Application in the catalytic enantioselective synthesis of 5-hydroxyisoxazolidines in batch and flow. Adv. Synth. Catal. 2018, 360, 2914-2924. (IF=5.8/Q1)
9. Junshan Lai, Yongping Liang, Teng Liu, Shouchu Tang. Dithiane induced cycloaddition/ aromatization tactic for the synthesis of multisubstituted furans. Org. Lett. 2016, 18, 2066-2069. (IF=6.07/Q1)
10. Junshan Lai, Lixia Tian, Yongping Liang, Yuan Zhang, Xingang Xie, Bowen Fang, Shouchu Tang. Di-tertbutyl peroxide mediated atom transfer radical addition of 2-chlorodithiane to aryl alkynes under mild conditions. Chem. Eur. J. 2015, 21, 14328–14331. (IF=5.02/Q2)
11. Junshan Lai, Lixia Tian, Xing Huo, Yuan Zhang, Xingang Xie, Shouchu Tang. Metal-free difunctionalization of alkynes with 2-chlorodithiane for synthesis of β-ketodithianes. J. Org. Chem. 2015, 80, 5894–5899.(IF=4.02/Q2)
12. Junshan Lai, Wenbin Du, Lixia Tian, Changgui Zhao, Xuegong She, Shouchu Tang. Fe-catalyzed direct dithioacetalization of aldehydes with 2-chloro-1, 3-dithiane. Org. Lett. 2014, 16, 4396–4399.(IF=6.07/Q1)