博士生导师

熊小东

姓名:熊小东

职称:副教授

邮箱:xiongxd@ncu.edu.cn

籍贯:江西南昌

导师类型:博士生导师

主讲课程:药物化学,药学导论

个人主页:

研究方向

不对称催化,具有潜在生物活性分子的合成及生物活性评价,绿色化学

教育经历

2009.9-2012.7 复旦大学 博士

2006.9-2009.7 复旦大学 硕士

2001.9-2005.7 南昌大学 学士

工作履历

2019.9~至今 南昌大学药学院

2013.4~2019.9 香港中文大学 博士后

2012.7~2013.4 先尼科(上海)化工有限公司 研发工程师

学术兼职

江西省药学会药物化学专业委员会副主任委员

个人荣誉

省级人才

主要业绩

  1. 主持科研课题:

[1] 基于仲铵离子对催化的不对称卤化反应研究(22061026), 国家自然科学基金,40万,2021.1-2024.12

[2]手性相转移催化的绿色不对称卤代反应研究(20212ACB213007),江西省杰出青年基金,20万,2021.7-2024.7

[3]有机催化的不对称卤代多环化构建螺环骨架的研究(20202BAB203004),江西省自然科学基金,2020.7-2023.6

2. 代表性论文:

[1] Xinzhe Wang, Zhipeng Wu, Guogang Tu, Yuanyue Zhao, Xiaodong Xiong. An efficient Selectfluor-mediated condensation of indoles and anthranilates for the synthesis of indoloquinazolinones. Chem. Commun. 2023, 59, 9368.

[2] Xinzhe Wang, Zhihuang Chen, Qingqing Liu, Wenqing Lin, Xiaodong Xiong. Amine organocatalysts for highly ortho-selective chlorination of anilines with sulfuryl chloride. Chem. Commun. 2022, 58, 13325.

[3] Xiaodong Xiong, Jonathan Wong, Ying-Yeung Yeung. Silver Salt-Mediated Allylation Reactions Using Allyl Bromides. J. Org. Chem. 2021, 86, 6974.

[4] Xiaodong Xiong, Tianyu Zheng, Xinyan Wang, Ying-Lung Steve Tse, Ying-Yeung Yeung. Access to Chiral Bisphenol Ligands (BPOL) through DesymmetrizingAsymmetric Ortho-Selective Halogenation. Chem 2020, 6, 919.

[5] Xiaodong Xiong, Ying-Yeung Yeung. Ammonium Salt Catalyzed Chem- and ortho-Selective Halogenation and Selenylation of Phenols and BINOLs. ACS Catal 2018,8, 4033.

[6] Xiaodong Xiong, Fei Tan, Ying-Yeung Yeung. Zwitterionic Salt Catalyzed Site-Selective mono-Bromination of Arenes. Org. Lett. 2017, 19, 4243.

[7] Xiaodong Xiong, Ying-Yeung Yeung. Highly Ortho-Selective Chlorination of Anilines Using Secondary Ammonium Salt Organocatalyst. Angew. Chem. Int. Ed. 2016, 55, 16101.

[8] Xiaodong Xiong, Chunlin Deng, Zhiming Li, Xiaoshui Peng, Henry N. C. Wong. Quasi-planar Diazadithio and Diazodiseleno[8]circulenens: Syntheses, Structures, and Properties. Org. Chem. Front. 2017, 4, 682.

[9] Xiaodong Xiong, Chun-Lin Deng, Boris. F. Minaev, G. V. Baryshnikov, Xiao-Shui Peng, Henry N. C. Wong. Tetraseleno and tetrathio[8]circulenes: Synthesis, structures and properties. Chem. Asian J. 2015, 10, 969.

[10] Xiaodong Xiong, Chunlin Deng, Xiaoshui Peng, Qian Miao, Henry N. C. Wong. Heteroatom-bridged Tetraphenylene: Synthesis, Structures and Properties. Org. Lett. 2014,16, 3252.

[11] Xiaodong Xiong, Yongwen Jiang, Dawei Ma. Assembly of N,N-Disubstituted Hydrazines and 1-Aryl-1H-indazoles via Copper-Catalyzed Coupling Reactions. Organic Lett. 2012. 14, 2552.