姓名:刘丹
职称:教授
邮箱:Liudan1201jx@ncu.edu.cn
籍贯:辽宁
导师类型:博士生导师
主讲课程:药理学
个人主页:
心血管药理;肿瘤药理;分子药理
1996.9~2001.7:江西医学院,临床医学专业,医学学士
2003.9~2006.7:南昌大学药学院,医学硕士
2006.9~2009.7:南昌大学,外科学专业,外科学博士
2009.10~2012. 10:江西省人民医院, 博士后
2014.5~2015.5:美国波士顿大学,访问交流
2001.7~至今:南昌大学药学院
中国药理学会会员
中国药理学会教学与科普专业委员会委员
中国药理学会来华留学生教学专业委员会常务委员
主持国家自然科学基金课题4项,主持省自然科学2项,中医药管理局重点项目1项。在国内外权威刊物发表学术论文40余篇,其中SCI收录论文20余篇。参编人民卫生出版及高等教育出版社书著3本。
1.主持的国家自然科学基金项目/课题
(1)国家自然科学基金委员会, 地区科学基金项目, 81760587, Bcl-2/VDAC1介导的线粒体凋亡途径在牛磺酸抗铁过载所致肝损伤中的作用, 2018-01-01 至 2021-12-31, 35万元,主持
(2)国家自然科学基金委员会, 地区科学基金项目, 81460551, 14-3-3γ/GSK3/β-catenin通路在内毒素耐受交叉保护心肌缺血/再灌注损伤中的作用, 2015-01-01 至 2018-12-31, 55万元, 主持
(3)国家自然科学基金委员会, 青年科学基金项目, 81100104, AMPKα2亚细胞定位在氯离子介导心肌缺血再灌注损伤中的机制研究, 2012-01-01 至 2014-12-31, 20万元, 主持
(4)国家自然科学基金委员会, 地区科学基金项目, 30860271, 心肌缺血再灌注损伤中ROS爆发性形成及其作用靶点与氯离子动态变化关系的研究, 2009-01-01 至 2011-12-31, 25万元, 主持
2.代表性论文
[1] (1)Zhao H, Ding T, Chen Y, Yang W, Rao J, Liu D, Yi B. Arecoline aggravates acute ulcerative colitis in mice by affecting intestinal microbiota and serum metabolites. Front Immunol. 2023; 14:1197922. (并列通讯作者)
[2] (2)Feng X, Hu W, Hong Y, Ruan L, Hu Y, Liu D. Taurine Ameliorates Iron Overload-Induced Hepatocyte Injury via the Bcl-2/VDAC1-Mediated Mitochondrial Apoptosis Pathway. Oxid Med Cell Longev. 2022; 2022: 4135752. (通讯作者)
[3] (3)He H , Qiao Y , Zhang Z , Wu Z , Liu D , Liao Z , Yin D , He M . Dual action of vitamin C in iron supplement therapeutics for iron deficiency anemia: prevention of liver damage induced by iron overload. Food Funct. 2018; 9(10): 5390-5401.
[4] (4)Liao Z, Liu D, Tang L, Yin D, Yin S, Lai S, Yao J, He M. Long-term oral resveratrol intake provides nutritional preconditioning against myocardial ischemia/reperfusion injury: involvement of VDAC1 downregulation. Mol Nutr Food Res. 2015; 59(3): 454-64
[5] (5)Zhang Z, Liu D, Yi B, Liao Z, Tang L, Yin D, He M. Taurine supplementation reduces oxidative stress and protects the liver in an iron-overload murine model. Mol Med Rep. 2014; 10(5): 2255-62. (并列第一)
[6] (6)Liu D, He H, Yin D, Que A, Tang L, Liao Z, Huang Q, He M. Mechanism of chronic dietary iron overload-induced liver damage in mice. Mol Med Rep. 2013; 7(4): 1173-9.
[7] (7)Yao X, Jiao S, Qin M, Hu W, Yi B, Liu D. Vanillic Acid Alleviates Acute Myocardial Hypoxia/Reoxygenation Injury by Inhibiting Oxidative Stress. Oxid Med Cell Longev. 2020; 2020: 8348035. (通讯作者)
[8] (8)Wan H, Liu X, Chen Y, Tang R, Yi B, Liu D. Silencing of the ARK5 gene reverses the drug resistance of multidrug-resistant SGC7901/DDP gastric cancer cells. PeerJ. 2020; 8: e9560. (通讯作者)
[9] (9)He H, Qiao Y, Zhou Q, Wang Z, Chen X, Liu D, Yin D, He M. Iron Overload Damages the Endothelial Mitochondria via the ROS/ADMA/DDAHII/eNOS/NO Pathway. Oxid Med Cell Longev. 2019; 2019: 2340392.
[10] (10)Zhu M, Deng W, Di S, Qin M, Liu D, Yi B. Gastrodin Protects Cardiomyocytes from Anoxia/Reoxygenation Injury by 14-3-3η. Oxid Med Cell Longev. 2018; 2018: 3685391. (通讯作者)
[11] (11)He H, Liu D, Lin H, Jiang S, Ying Y, Chun S, Deng H, Zaia J, Wen R, Luo Z. Phosphatidylethanolamine binding protein 4 (PEBP4) is a secreted protein and has multiple functions. Biochim Biophys Acta. 2016; 1863(7 Pt A): 1682-9.
[12] (12)Liu D, He M, Yi B, Guo WH, Que AL, Zhang JX. Pim-3 protects against cardiomyocyte apoptosis in anoxia/reoxygenation injury via p38-mediated signal pathway. Int J Biochem Cell Biol. 2009 Nov; 41(11): 2315-22.